Allergy, Nose & Sinus
Can Fungus Infections in Your Sinus Cause Headaches?
February 10, 2020
Understanding Fungal Sinusitis
Fungal sinusitis refers to a variety of sinus infections caused by fungi. While our bodies naturally host various microorganisms, including fungi, these usually don’t cause problems. However, under certain conditions, fungi can overgrow in the sinuses, leading to inflammation and infection. This can manifest in several ways, from relatively minor discomfort to more serious complications.
Case Study: Headache Resulting From Fungal Infection in Sinus
Dr Gan recently treated a patient, Ms A, an 18-year-old who presented with persistent headaches and constant heaviness in the central/back part of her head for several months. She also suffered from a blocked left nostril, frequent postnasal drip, and had been coughing out clumps of brown material. Although she had undergone multiple courses of oral antibiotics, her symptoms failed to resolve.
After performing a nasal endoscopy, it was revealed that she had mucopus (mucous mixed with pus) in her left nasal cavity. The mucopus was suctioned out, and a large polyp was visible.

Mucous and some pus filling up most of the left nasal cavity.

After suctioning the mucopus, a large polyp can be seen.
Given the polyp’s unilateral (one-sided) presentation, a CT scan was performed to rule out a tumour, and the nasal polyp was sent for a biopsy. The CT scan revealed a complete blockage of the left sphenoid sinus (the sinus behind the eyes, close to the brain), suggesting possible fungal concretions, and the biopsy confirmed an inflammatory polyp (non-cancerous).
Since the sphenoid sinus is one of the deepest sinuses in the head and is located close to vital structures, including the brain, nerves and major blood vessels, prompt treatment was essential to prevent the infection from spreading to these critical areas.

A CT scan of the head (axial cut) showing complete opacification (blockage) of the left sphenoid sinus
Ms A then underwent a left Functional Endoscopic Sinus Surgery (FESS) to remove the inflammatory polyp and drain the blocked sinus. During the procedure, fungal concretions (clumps of fungus) that were completely filling up the left sphenoid sinus were subsequently removed. The lining of her sinus was inflamed due to the long-standing infection.

Fungal ball (fungal concretions) in the left sphenoid sinus during surgery

Fungus removed from the nose

Fungus removed from the nose
One month post-surgery, Ms A’s left sphenoid sinus was completely healed, and her headaches and postnasal drip had resolved.


What Causes Fungal Sinusitis?
While the exact reasons why some individuals develop fungal balls in the sinus remain unclear, several factors can contribute.
Fungal balls most commonly occur in the maxillary (cheek) sinus, and a history of dental procedures is a known risk factor. These fungal collections can become a source of secondary bacterial infection and may completely obstruct the sinus, as seen in Ms. A’s case.
Fungal sinusitis can also arise from various other causes, including weakened immune systems, allergies, and environmental exposures. Fungal sinusitis can take various forms, including sinus fungal ball, invasive fungal sinusitis (more common in immunocompromised individuals), and allergic fungal sinusitis.
Symptoms of Fungal Sinusitis
Headaches are a common symptom of fungal sinusitis, especially when the sphenoid sinus is involved. However, a fungal sinus infection can also cause:
- Facial pain or pressure
- Nasal congestion or blockage
- Postnasal drip
- Discoloured nasal discharge (yellow, green, or brown)
- Loss of smell
- Cough
- Ear pain or fullness
Treatment for Fungal Sinusitis
The treatment for fungal sinusitis typically involves surgical removal of the infection. FESS, a minimally invasive procedure performed through the nose, is a common and effective option, with most patients experiencing significant symptom relief afterwards. In some cases, additional antifungal medication may also be prescribed, especially if the infection is of a more invasive form.
If you are experiencing any of the above symptoms, please consult an experienced ear, nose and throat specialist in Singapore for a thorough evaluation and personalised treatment plan. They can help diagnose sinus conditions, including fungal sinusitis, and provide a sinusitis cure to address your needs.